As part of a webinar entitled Burden of HDV: A leap in the dark, Professor Pietro Lampertico, Director of the Gastroenterology and Hepatology Division, University of Milan and Dr Ivana Carey, Clinical Lecturer in Viral Hepatitis, Kings College London provided an overview of HDV infection, including the latest thinking on pathogenesis, natural history and epidemiological data from a global and national perspective. Professor Lampertico also discussed triple-infection with HBV, HDV and human immunodeficiency virus (HIV). Dr Carey focussed on clinical challenges and proposed potential solutions to identify and monitor patents. Dr David Bell, Consultant in Infectious Diseases, Queen Elizabeth University Hospital, Glasgow joined the two experts for a discussion chaired by Professor Stephen Ryder, Director of Research and Innovation, Nottingham University Hospitals. They discussed the current status, knowledge, challenges and gaps in HDV epidemiology in the UK and potential solutions.
Nearly 50 years after HDV discovery: knowns and unknowns
Recorded: April 27th 2023
Duration: 26:04
Speaker biographies
Professor Pietro Lampertico

Professor Pietro Lampertico
Professor Pietro Lampertico is the Director of the Gastroenterology and Hepatology Division, and Head of the Center for Liver Disease at the University of Milan. He has spoken internationally about liver disease, specifically the natural history of HBV and antiviral treatment of HBV and HDV, and has published several articles and book chapters. He is currently involved in national and international HBV and HDV clinical trials.
Dr Ivana Carey

Dr Ivana Carey
Dr Carey has a special interest in novel HBV infection biomarkers including their implementation into diagnostics and clinical management, HBV novel therapies leading to ‘functional cure’ – investigator and sub-investigator in phase 1–4 clinical trials. She is highly experienced in the management of viral infections during and post pregnancy including prevention of transmission from mother to child (UK guidelines), member of national HCV paediatric MDT ODN.
Dr David Bell

Dr David Bell
Dr Bell is a Consultant in Infectious Diseases and Acute Medicine working in Glasgow, UK and trained in Liverpool before taking up his Consultant post in 2010. Dr Bell looks after inpatients as well as running regular outpatient HIV and Hepatitis clinics. He leads the commercial clinical trial work in blood-borne viruses and has been a Principal Investigator for multiple Hep C, Hep B, and HIV treatment trials. Clinical interests include Hepatitis B, HIV as well as tropical infections.
Professor Stephen Ryder

Professor Stephen Ryder
Professor Stephen Ryder is lead clinician for the Hepatitis C NHS England Operational Delivery Network and Director of Research and Innovation at Nottingham University Hospitals. His major clinical and research interest is hepatitis C infection and large clinical trials in hepatology. Professor Ryder was recognised as one of the leading recruiters to commercial clinical trials in the “NIHR at 10” awards. Professor Ryder was the national lead for the Hepatology Clinical Research Network until 2015 and is now the Co-Director of the East Midlands CRN.
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Date of preparation February 2025