As part of a webinar entitled Burden of HDV: A leap in the dark, Dr Ivana Carey, Clinical Lecturer in Viral Hepatitis, Kings College London presented the impact of HDV on liver disease progression in people living with HBV, compared to those living with HBV mono-infection. Dr Carey shared data around the associations between HDV genotype and progression, prognosis, emergence of complications, mortality, adverse outcomes and treatment response for the established current management options. Dr Carey also discussed studies on hepatocellular carcinoma pathogenesis in HBV-HDV co-infection, the mechanisms and pathways involved and data on HBV-HDV-HIV triple-infection. Evidence on the role of transplantation in HBV-HDV co-infection was presented.
A small virus, a big threat
Recorded: April 27th 2023
Duration: 15:54
Speaker biographies
Dr Ivana Carey

Dr Ivana Carey
Dr Carey has a special interest in novel HBV infection biomarkers including their implementation into diagnostics and clinical management, HBV novel therapies leading to ‘functional cure’ – investigator and sub-investigator in phase 1–4 clinical trials. She is highly experienced in the management of viral infections during and post pregnancy including prevention of transmission from mother to child (UK guidelines), member of national HCV paediatric MDT ODN.
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UKI-HPX-0047
Date of preparation February 2025